I’ve got a USB-to-Serial cable that I bought from Radio Shack that allows me to use my notebook’s USB port to cable in to devices like our managed switches and our phone system. I was afraid that I might have to replace the cable when I realized that it doesn’t have Vista drivers for it.
However, if you go here, you’ll find a forum post with a fix for this. I downloaded the fix and attempted driver installation, and things are working just fine now.
Just thought I would throw this out in case anyone else is using one of these cables.